Symbol
Name
ID

Lmna
lamin A
MGI:96794

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes

Diabetes mellitus

Insulin-resistant diabetes mellitus

Type II diabetes mellitus

Hyperinsulinemia

Pancreatitis

Acute pancreatitis

Decreased serum leptin

Thyroid carcinoma

Pubertal developmental failure in females

Delayed menarche

Precocious puberty

Hypogonadism

Female hypogonadism

Hypergonadotropic hypogonadism

Disease(s) Associated with LMNA

dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome

familial partial lipodystrophy type 2

mandibuloacral dysplasia type A lipodystrophy

progeria

type 2 diabetes mellitus

Werner syndrome

Mouse Phenotypes		small thymus	thymus atrophy	decreased sebaceous gland number	sebaceous gland hypoplasia	decreased eccrine gland number	small seminiferous tubules	small testis
Availability	Mouse Genotype	small thymus	thymus atrophy	decreased sebaceous gland number	sebaceous gland hypoplasia	decreased eccrine gland number	small seminiferous tubules	small testis
	Lmna^Dhe/Lmna^Dhe
	Lmna^tm1.1Otin/Lmna^tm1.1Otin
	Lmna^tm1Rben/Lmna^tm1Rben
	Lmna^tm1Stw/Lmna^tm1Stw
	Lmna^tm2Stw/Lmna^tm2Stw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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